The origin and possible functions of local three-stranded DNA-RNA hybrid regions in the mammalian genome is still a matter of discussion. R-loops have been so far essentially detected by immunodetecti
Predicted R-loops specifically detected in 3T3 and E14 were generated by selecting genome bins that were assigned probabilities ≥ 0.9 when applied one cell line model and ≤ 0.1 when applied the other.