Crystal Structure of PI3Kalpha in complex with fragments 12 and 15
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Crystal Structure of PI3Kalpha in complex with fragments 12 and 15 Descriptor: 6-methylpyridin-2-amine, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... Authors: Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. Deposit date: 2016-08-09 Release date: 2017-02-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.47 Å) Cite: Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Bioorg. Med. Chem., 25, 2017
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2016-08-09
