Background Niclosamide, an FDA-approved anti-helminthic drug, has activity in preclinical models of castration-resistant prostate cancer (CRPC). Potential mechanisms of action include degrading consti

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Additional file 13: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

药物重定位

癌症治疗

is a table listing predicted drug candidates for breast and prostate cancer using LINCS dataset. (XLSX 1152 kb)

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Dataset variants used in "Task-Driven Knowledge Graph Filtering Improves Prioritizing Drugs for Repurposing"

药物重定位

知识图谱过滤

This file contains all datasets and variants thereof used in the linked paper. We do not take credit for constructing the datasets, which has been done by the respective original authors (https://gith

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Clemastine suppresses proneural glioblastoma stem cell growth II. Clemastine suppresses proneural glioblastoma stem cell growth II

胶质瘤靶向治疗

药物重定位

Glioblastoma (GBM) cells’ stemness-like features and lineage plasticity promote tumor progression. Here, we demonstrate that Clemastine, a drug for treating hay fever and allergy symptoms, effectively

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Pathway similarity scores

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