Multi-organ profiles of C fiber degenerated (KPCF) mice and respiratory syncytial virus (RSV)-infected KPCF mice

Stimulation of unmyelinated C-fibers is able to initiate host responses. In this study, we established the model of C fiber degenerated (KPCF) mice. KPCF mice were given respiratory syncytial virus (RSV) infection. We aimed to figure out the role of C fibers in RSV infection. Lung, intestine, brain, and spleen tissues from six KCF mice (6 - 8 weeks old; three in KCF group and three in RSV-infected KCF group) were subjected to RNA sequencing