Crystal structure of TEAD2 bound to Compound 2
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Crystal structure of TEAD2 bound to Compound 2 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-{5-[(E)-2-(4,4-difluorocyclohexyl)ethenyl]-6-methoxypyridin-3-yl}methanesulfonamide, Transcriptional enhancer factor TEF-4 Authors: Noland, C.L, Holden, J.K, Crawford, J.J, Zbieg, J.R, Cunningham, C.N. Deposit date: 2019-11-12 Release date: 2020-06-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.658 Å) Cite: Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling. Cell Rep, 31, 2020
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2019-11-12
