Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner

ChEBI2011-04-26 更新2026-07-21 收录

干细胞稳态调控

细胞非自主性调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21700 数据链接链接失效反馈

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Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner

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2011-04-26

Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homesotasis [Single Cells]

干细胞稳态调控

单细胞转录组学

Hematopoietic stem cells (HSCs) balance self-renewal and differentiation to maintain hematopoietic fitness throughout life. In steady-state conditions, HSC exhaustion is prevented by the maintenance o

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MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells. MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells

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Haematopoietic stem cells (HSCs) tightly regulate their quiescence, proliferation, and differentiation to generate blood cells during the entire lifetime. The mechanisms by which these critical activi

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Effect of Copper deficiency on gene expression of Lin-c-Kit cell in the bone marrow of mice

干细胞稳态调控

铜代谢调控

Copper homeostasis has been linked to human health and hematopoiesis. However, the underlying mechanisms remain elusive. Here, we demonstrate the pivotal role of the transporter Slc31a1(Ctr1) in coppe

NIAID Data Ecosystem10

Ssb1 and Ssb2 have essential and overlapping functions in adult stem cell homeostasis - granulocyte-macrophage progenitor data.

干细胞稳态调控

基因组稳定性

The single-stranded DNA binding proteins SSB1 and SSB2 are crucial regulators of the DNA damage response, however the overlapping functions of these related proteins is incompletely understood. We gen

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Competition between hematopoietic stem and progenitor cells controls the hematopoietic stem cell homeostasis [bulk RNA-seq]

干细胞稳态调控

细胞竞争机制

Cellular competition for limiting hematopoietic factors is a physiologically regulated but poorly understood process. Here, we studied this phenomenon by hampering hematopoietic progenitor access to L

NIAID Data Ecosystem20

Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner

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