官方服务：
资源简介：
HDL suppresses the type I interferon response
应用场景：
创建时间：
2010-10-01
相关数据集
The Type I interferon response impairs differentiation potential of pluripotent stem cells [RT-qPCR]. The Type I interferon response impairs differentiation potential of pluripotent stem cells [RT-qPCR]
Upon virus infection,pluripotent stem cells neither induce nor respond to canonical Type I interferons (IFN-I). To better understand this biology,we characterized induced pluripotent stem cells (iPSCs
NIAID Data Ecosystem60
DataSheet_1_Janus Kinase Inhibitors in the Treatment of Type I Interferonopathies: A Case Series From a Single Center in China.docx
ObjectiveThis study aimed to assess the efficacy and safety of 2 Janus kinase (JAK) inhibitors (jakinibs) tofacitinib and ruxolitinib in the treatment of type I interferonopathies patients including S
NIAID Data Ecosystem50
Induction of Noxa-Mediated Apoptosis by Modified Vaccinia Virus Ankara Depends on Viral Recognition by Cytosolic Helicases, Leading to IRF-3/IFN-β-Dependent Induction of Pro-Apoptotic Noxa
Viral infection is a stimulus for apoptosis, and in order to sustain viral replication many viruses are known to carry genes encoding apoptosis inhibitors. F1L, encoded by the orthopoxvirus modified v
NIAID Data Ecosystem10
Type 1 interferons induce changes in core metabolism that are critical for immune function. Mus musculus
Type 1 interferons (IFNs) induce complex responses that can be beneficial or deleterious, depending on context. Greater understanding of the mechanisms of action of these cytokines could allow new the
NIAID Data Ecosystem50
In vivo protection against endotoxin by plasma high density lipoprotein.
Overwhelming bacterial infection is accompanied by fever, hypotension, disseminated intravascular coagulation, and multiple organ failure leading to death in 30-80% of cases. These classical symptoms
PubMed Central1993-12-15 更新20
