Association of IL6R haplotypes in block 1 and block 2 with differences in serum CRP levels (compared to the reference haplotype where mean CRP (95%CI) are shown) in controls from the SHEEP and PROCARDIS and in block 2 from the IMPROVE study.

Data represent the mean and relative 95%CI of the difference in serum CRP levels (mg/L) observed in the presence of one copy of each haplotype configurations as compared to the reference haplotype. Genotype data from only three SNPs in block 2 were available in the IMPROVE study (rs7553796 C/A (pairwise LD with rs4553185T/C, r2 = 0.96) rs8192284A/C and rs4072391T/C (pairwise LD with rs7514452T/C r2 = 0.98).Association of IL6R haplotypes in block 1 and block 2 with differences in serum CRP levels (compared to the reference haplotype where mean CRP (95%CI) are shown) in controls from the SHEEP and PROCARDIS and in block 2 from the IMPROVE study.