This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which al

reactome.org20

Over-expression of Trib1 overcomes self-degradation to induce myeloid leukemia

急性髓系白血病

蛋白质降解

Cop1 encodes a ubiquitin E3 ligase that is well preserved during evolution both in plants and metazoan. In metazoan, C/EBP family transcription factors are Cop1 targets for degradation, and the proces

NIAID Data Ecosystem10

Data_Sheet_3_Profiling of Protein Degraders in Cultures of Human Gut Microbiota.docx

结肠微生物群

蛋白质降解

Unabsorbed proteins reach the colon and are fermented by the microbiota, yielding a variety of harmful metabolites. In the present study, a 16S rRNA gene survey identified the bacterial taxa flourishi

NIAID Data Ecosystem40

SCF AtPP2-B11 modulates ABA signaling by facilitating SnRK2.3 degradation in Arabidopsis thaliana

植物ABA信号转导

蛋白质降解

The phytohormone abscisic acid (ABA) is an essential part of the plant response to abiotic stressors such as drought. Upon the perception of ABA, pyrabactin resistance (PYR)/PYR1-like (PYL)/regulatory

NIAID Data Ecosystem20

Molecular modelling supporting data for macrocycle-based PROTACs targeting cyclophilin A

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