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Additional file 14 of Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma

Figshare2022-09-24 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Additional_file_14_of_Intratumor_heterogeneity_and_T_cell_exhaustion_in_primary_CNS_lymphoma/21203320 数据链接链接失效反馈

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资源简介：

Additional file 14: Table S12. Published exhaustion gene signatures.

应用场景：

创建时间：

2022-09-24

肿瘤免疫学

细胞毒性机制

T cells and their effector functions, in particular the canonical cytotoxicity of CD8+ T cells involving perforin, granzymes, Fas Ligand, and TRAIL, are crucial for tumor immunity. Here, we reveal a

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Tox reinforces the phenotype and longevity of exhausted T-cells in chronic viral infection [day28 acute vs chronic]. Tox reinforces the phenotype and longevity of exhausted T-cells in chronic viral infection [day28 acute vs chronic]

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Chronic CD8 T-cell stimulation in persisting infections or tumors can induce a stable gene expression program, known as T-cell dysfunction or exhaustion, that limits the cell’s effector functions and

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Altered binding of tumor antigenic peptides to MHC class I affects CD8 T cell effector responses

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T cell priming occurs when a naÃ¯ve T cell recognizes cognate peptide-MHC complexes on an activated antigen presenting cell. The circumstances of this initial priming have dramatic ramifications on th

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RNA sequencing of tissue resident macrophages, progenitors and tumor cells from murine head and neck tumors

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RNA测序

We report the RNA sequences of bone marrow derived and tissue resident macrophages and their progenitor cells from murine head and neck tumors We found that tissue resident macrophages express signatu

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Neonatal CD8+ T cells resist terminal exhaustion during chronic infection. Neonatal CD8+ T cells resist terminal exhaustion during chronic infection

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This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

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