Melanoma C32 ENU Resistance to Single Agent Therapy

NIAID Data Ecosystem2026-03-10 收录

肿瘤耐药机制

靶向治疗筛选

数据链接：

https://www.omicsdi.org/dataset/ega/EGAS00001001697 数据链接链接失效反馈

官方服务：

资源简介：

This study involves mutagenizing C32, a melanoma cell line, with ENU to identify those mutations which engender resistance to a targeted treatment.EGA study EGAS00001001697

创建时间：

2017-07-26

6mer Seed toxicity and platinum resistance in ovarian cancer [DISE-26]. 6mer Seed toxicity and platinum resistance in ovarian cancer [DISE-26]

肿瘤耐药机制

RNA功能研究

We demonstrate that 6mer seed toxicity plays a role in platinum resistance of ovarian cancer Overall design: Small RNA was isolated from A2780 and Pt resistant A2780R ovarian cancer cells

NIAID Data Ecosystem30

Differentiation of DLBCL induced by HDAC inhibitors is associated with sensitization to proteasome inhibition. Homo sapiens

肿瘤耐药机制

靶向治疗联合方案

Epigenetic modifying enzymes are commonly mutated in diffuse large B cell lymphoma (DLBCL), suggesting that epigenetic regulation is an important factor in DLBCL pathogenesis and a potential target fo

NIAID Data Ecosystem20

Multiomic Profiling of Tyrosine Kinase Inhibitor-Resistant K562 Cells Suggests Metabolic Reprogramming To Promote Cell Survival

肿瘤耐药机制

代谢重编程

Resistance to chemotherapy can occur through a wide variety of mechanisms. Resistance to tyrosine kinase inhibitors (TKIs) often arises from kinase mutationshowever, “off-target” resistance occurs bu

NIAID Data Ecosystem10

EGAS00001001304-sc-20151202 - samples

肿瘤耐药机制

BRAF靶向治疗

2 BRAFV600E cell lines that have been made resistance to 1. the BRAF inhibitor PLX4720 and 2. the combination therapy of dabrafenib and trametinib seem to have a internal duplication in the kinase dom

NIAID Data Ecosystem20

Gene expression of PC9 and PC9-OR cell line [JXQ_RNA]. Gene expression of PC9 and PC9-OR cell line [JXQ_RNA]

肿瘤耐药机制

转录组分析

To investigate the abnormal gene expression in Osimertinib Resistance lung cancer cell line, We performed gene expression profiling analysis using data obtained from RNA-seq of PC9 cell line and PC9-O

NIAID Data Ecosystem20

Melanoma C32 ENU Resistance to Single Agent Therapy

资源简介：

相关数据集