HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease
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资源简介:
Human DLE demonstrates expression of HIF1- and cytotoxic molecules including granzyme B in the DLE lymphocytic infiltrate. Normalized gene expression per region of interest (ROI) in DLE or normal control skin (n = 3 patients, 3 ROIs per patient) as characterized by Nanostring GeoMx Digital Spatial Profiling. ROIs were selected to include T cell rich infiltrate. Cancer Transcriptome Atlas RNA probe set used.
创建时间:
2024-01-01



