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CRISPR-mediated biocontainment: Data for figure 1B

NIAID Data Ecosystem2026-03-11 收录

基因编辑安全性

细胞疗法生物防护

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA604267 数据链接链接失效反馈

官方服务：

资源简介：

Leveraging transposable elements of the genome to prevent Cas9 editing and design a safety-switch for cell therapies

应用场景：

创建时间：

2020-01-31

基因编辑安全性

核酸酶脱靶检测

We describe a robust linear amplification-mediated high-throughput genome-wide translocation sequencing (HTGTS) method that identifies endogenous or ectopic "prey" DNA double-stranded breaks (DSBs) ac

NIAID Data Ecosystem60

Additional file 1 of Deep learning improves the ability of sgRNA off-target propensity prediction

CRISPR脱靶预测

基因编辑安全性

Additional file 1. Detailed comparison results for sgRNA off-target propensity prediction.

Figshare2020-02-11 更新30

Improving the sensitivity of in vivo CRISPR off-target detection through DNA repair inhibition. Homo sapiens and Mus musculus

CRISPR脱靶检测

基因编辑安全性

Improving the sensitivity of in vivo CRISPR off-target detection through DNA repair inhibition

NIAID Data Ecosystem30

Frequency and mechanisms of LINE-1 retrotransposon insertions at CRISPR/Cas9 sites

基因编辑安全性

逆转录转座子转录

CRISPR/Cas9-based genome editing has revolutionized experimental molecular biology and entered the clinical world for targeted gene therapy. Identifying DNA modifications occurring at CRISPR/Cas9 targ

NIAID Data Ecosystem40

Transfer of mitochondrial DNA into the nuclear genome during gene editing [target sequencing]

基因编辑安全性

线粒体DNA

Mitochondria serve as the cellular powerhouse, and their distinct DNA makes them a prospective target for gene editing to treat genetic disorders. However, the impact of genome editing on mitochondria

NIAID Data Ecosystem30

CRISPR-mediated biocontainment: Data for figure 1B

资源简介：

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