Univariate and multivariate analysis of factors associated with survival and recurrence.

*Patients were classified into four groups according to their intratumoral α-SMA density and MVD: group I (n = 68), both low density; group II (n = 84), high α-SMA density and low MVD; group III (n = 86), low α-SMA density but high MVD; and group IV (n = 67), both high density. †Group I (n = 14), both low density; group II (n = 15), high α-SMA density and low MVD; group III (n = 13), low α-SMA density but high MVD; and group IV (n = 15), both high density. ‡The multivariate analysis of different subgroups of α-SMA and MVD was analyzed together with other risk factors identified by univariate analysis but excluding α-SMA and MVD themselves, in order to avoiding the interference of them on the combinational group. Abbreviations: OS, overall survival; RFS, recurrence free survival; HR, hazard ratio; CI, confidence interval; HCC, hepatocellular carcinoma; HBeAg, hepatitis B e antigen; TNM, tumor-node-metastasis; α-SMA, alpha-smooth muscle actin; MVD, microvessel density; PC, pancreatic cancer; NA, not adapted; NS, not significant.