Crystal structure of PIM1 in complex with a Pyrrolo-Pyrazinone compound
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Crystal structure of PIM1 in complex with a Pyrrolo-Pyrazinone compound Descriptor: (4~{S})-4-(2-azanylethyl)-6-phenyl-7-[3-(trifluoromethyloxy)phenyl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1-ol, Isoform 2 of Serine/threonine-protein kinase pim-1 Authors: Casale, E. Deposit date: 2022-05-12 Release date: 2022-10-05 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Stereoselective synthesis of 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives as PIM kinase inhibitors inspired from marine alkaloids. Chirality, 34, 2022
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2022-05-12
