Ionizing radiation promotes cytosolic DNA sensing and consequent antitumor immune responses. But how tumor cell-intrinsic cytosolic DNA sensing is initiated by radiation remains poorly defined. Here,
Apoptosis plays an important role in the normal life activities of cells. The classic view of apoptosis is that after caspase is activated, apoptosis is inevitable. When the apoptosis-inducing agent i
Early and late apoptosis measured by annexin V and propidium iodide staining in human breast cancer cells revealed that the metastatic MDA-MB-231 cells pretreated for 24 h with artesunate, became resi
Table S1. Molecular characterization of epithelial ovarian cancer cell lines, SKOV3, Kuramochi, and OVCAR3. To provide additional detail regarding the epithelial ovarian cancer cell lines used in this
The essential roles of PCNA as a scaffold protein in DNA replication and repair are well established, while its more recently discovered cytosolic roles are less explored. Alpha-enolase (ENO1) and 6-p