Colorectal cancer (CRC) is one of the most prevalent cancers, with more than one million new cases every year worldwide. The prognosis of CRC considerably depends on its disease stage and metastatic s
In patients with advanced colorectal cancer, leucovorin, fluorouracil, and irinotecan (FOLFIRI) is considered as one of the reference first-line treatments. However, only about half of treated patient
Colorectal cancer is a heterogeneous disease molecularly characterized by inherent genomic instabilities, chromosome instability and microsatellite instability. In the present study we propose transcr
