Mycobacterium tuberculosis strains of particular sublineages of Lineage 4 (previously known as the Euro-American lineage) are isolated from all regions in the world, whereas strains of other sublineag
Tuberculosis (TB) has surpassed HIV as the leading infectious disease killer worldwide since 2014. The main pathogen, Mycobacterium tuberculosis (Mtb), contains ~4,000 genes that account for ~90% of t
PacBio sequencing was used to sequence and assembly genomes from clinical M. tuberculosis isolates. The PacBio genome assemblies were then used to benchmark variant calling performance of short-read I