Purpose: The goal of this study is to reveal the transcriptional dynamics of hamster liver upon DC371739 treatment Methods: Total RNAs were extracted from the livers of HFD-hamsters control and DC3717

NIAID Data Ecosystem50

The STAT3-SETDB2 Axis Dictates NF?B-mediated Inflammation in Macrophages during Wound Repair

细胞表观遗传调控

糖尿病伤口愈合机制

Macrophage transition from an inflammatory to reparative phenotype after tissue injury is controlled by epigenetic enzymes that regulate inflammatory gene expression. We have previously identified the

NIAID Data Ecosystem40

m 6 A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin

糖尿病伤口愈合机制

RNA修饰与自噬调控

Dysregulation of macroautophagy/autophagy contributes to the delay of wound healing in diabetic skin. N6-methyladenosine (m6A) RNA modification is known to play a critical role in regulating autophagy

NIAID Data Ecosystem70

Mesenchymal stem cell-derived small extracellular vesicles promoting M2 macrophage polarization through p38 MAPK inhibition

干细胞免疫调控

糖尿病伤口愈合机制

To investigate how mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) promotes diabetic wound healing through macrophage M1-to-M2 polarization, we conducted RNA-seq to search for th

Mendeley Data40

Rat Skin Transcriptome Sequencing

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