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Implicating effector genes at COVID-19 GWAS loci using promoter-focused Capture-C in disease-relevant immune cell types [RNA-seq]

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NIAID Data Ecosystem2026-05-01 收录
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To investigate the potential role of COVID-19 severity associated GWAS hits affecting the cis-regulatory architecure of human immune cell types. We used high-resolution chromatin conformation capture and accessibility to identify potential effector genes Overall design: We performed ATAC-seq, RNA-seq, and Promoter Focused Capture C on Naïve B and GCB cells

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2024-04-18
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