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Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation

NIAID Data Ecosystem2026-03-14 收录

数据链接：

https://figshare.com/articles/dataset/Molecular_sensing_of_mechano-_and_ligand-dependent_adhesion_GPCR_dissociation/21930960 数据链接链接失效反馈

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资源简介：

Raw data of Western blots in Scholz, Dahse et al.

应用场景：

创建时间：

2023-03-09

生物传感器

GPCR信号传导

Data set for "Improved split TEV GPCR beta-arrestin recruitment assays via systematic analysis of signal peptide and a beta-arrestin binding motif variants" as published in Wu et al., Biosensors 2023,

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Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling

GPCR信号传导

糖基化功能研究

The G protein-coupled receptor (GPCR) Smoothened (Smo) is the requisite signal transducer of the evolutionarily conserved Hedgehog (Hh) pathway. Although aspects of Smo signaling are conserved from Dr

NIAID Data Ecosystem70

The raw data for Fig 4A and 4B.

GPCR信号传导

治疗药物开发

Chemokine-like receptor 1 (CMKLR1), also known as chemerin receptor 23 (ChemR23) or chemerin receptor 1, is a chemoattractant G protein–coupled receptor (GPCR) that responds to the adipokine chemerin

Figshare2023-12-06 更新20

Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family

GPCR信号传导

蛋白质相互作用

G protein-coupled receptors (GPCRs) are the largest receptor superfamily that can propagate various extracellular stimulus into cells by coupling with heterotrimeric G proteins. G proteins are divided

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Synaptamide activates the adhesion GPCR GPR110 through conformational changes induced by GAIN domain binding

GPCR信号传导

神经活性配体机制

Ligand-induced conformational changes of GPR110 in cells probed by chemical cross-linking and mass specrtometry

NIAID Data Ecosystem20