Astrocytic tumors, including glioblastomas, exhibit aggressive behavior and poor outcomes, with TGF-β isoforms playing key roles in their progression. This study highlights the differential expression
The majority of oligodendrogliomas exhibit an intrinsic tendency to develop into malignant high-grade tumors. Angiogenesis is a major factor contributing to the malignant transformation of oligodendro
YAP1 gene fusions have been observed in a subset of paediatric ependymomas. Here we show that ectopic expression of active nuclear YAP1 (nlsYAP5SA) in ventricular zone neural progenitor cells using c
Neurocognitive dysfunction is the leading cause of a reduced quality of life in patients with primary brain tumors. However, how the human brain responds to the tumor and its treatment remains largely
The raw dataset of this study contained the gene alterations, clinical informations and survival data of glioma patients. Gene alterations data were obtained by Next-generation DNA sequencing of gliom
