MCL1
收藏rgd.mcw.edu2025-01-21 收录
官方服务：
资源简介：
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
本基因编码一种抗细胞凋亡蛋白，该蛋白属于Bcl-2家族成员。可变剪接导致多种转录本变体的产生。最长的基因产物（异构体1）通过抑制细胞凋亡来增强细胞存活，而可变剪接产生的较短基因产物（异构体2和异构体3）则促进细胞凋亡，具有诱导细胞死亡的作用。[由RefSeq提供，2010年10月]
提供机构：
Rat Genome Database
