Identification of DEK as a potential therapeutic target for Neuroendocrine prostate cancer

ChEBI2015-01-15 更新2026-07-21 收录

神经内分泌前列腺癌

药物靶点发现

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-61214 数据链接链接失效反馈

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Identification of DEK as a potential therapeutic target for Neuroendocrine prostate cancer

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2015-01-15

Table_1_Exploring novel targets of sitagliptin for type 2 diabetes mellitus: Network pharmacology, molecular docking, molecular dynamics simulation, and SPR approaches.docx

药物靶点发现

糖尿病机制

BackgroundDiabetes has become a serious global public health problem. With the increasing prevalence of type 2 diabetes mellitus (T2DM), the incidence of complications of T2DM is also on the rise. Sit

NIAID Data Ecosystem20

Crystal structure of T brucei phosphodiesterase B2 bound to compound 13e

结构生物学

药物靶点发现

Crystal structure of T brucei phosphodiesterase B2 bound to compound 13e Descriptor: (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[2-(2-oxidanylideneimidazolidin-1-yl)ethoxy]phenyl]-4~{a},5,8,8~

Protein Data Bank Japan2023-11-08 更新10

crystal structure of compound 16 bound to MDM2(17-111), {(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-(PYRROLIDIN-1-YLSULFONYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL}ACETIC ACID

结构生物学

药物靶点发现

Protein Data Bank Japan2024-02-28 更新10

X-Ray structure of CLK2-KD(136-496)/Indazole1 at 2.39A

抑制剂结构

药物靶点发现

X-Ray structure of CLK2-KD(136-496)/Indazole1 at 2.39A Descriptor: (2~{S})-4-methyl-1-[5-(3-methyl-2~{H}-indazol-5-yl)pyridin-3-yl]oxy-pentan-2-amine, Dual specificity protein kinase CLK2 Authors: Kal

Protein Data Bank Japan2024-01-17 更新20

Structure of UDP-glucose 4-epimerase from Brucella abortus

病原体结构解析

药物靶点发现

Structure of UDP-glucose 4-epimerase from Brucella abortus Descriptor: NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION Authors

Protein Data Bank Japan2023-12-27 更新10

Identification of DEK as a potential therapeutic target for Neuroendocrine prostate cancer

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