Additional file 3 of Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression

Additional file 3: Table S1. Genomic and statistical information of the highly expressed circRNAs in K562 and HepG2. First six columns provide circRNA_ID, genomic positions of circRNAs, and information of circRNAs found in circBase. BSJ_reads and linear_reads give the number of reads supporting the circRNA and its corresponding linear transcript based on the CIRI2 pipeline. BSJ_reads_CIRCexplorer holds the number of reads supporting the circRNA by the CIRCexplorer pipeline. Exonic_length and N_exons hold the exonic length of the circRNA and the number of exons comprising the circRNA. N_RBPs give the number of RBPs with binding sites in the exonic part of the circRNA. RBP_overlap_bp is the number of bp overlapped by RBP binding sites (merged) in the exonic part of the circRNA. RBP_coverage is the fraction of the circRNA (exonic part) covered by RBP binding sites (RBP_overlap_bp/exonic_length*100). N_non_circ_exon_host_gene indicates the number of non-circularizing exons in the host gene. The mean RBP-coverage of non-circularizing exons in the host gene is provided in the column mean_RBP_coverage_non_circ_exons and was added a pseudo count of 1 to calculate the ratio between circRNA RBP-coverage and RBP-coverage of non-circ-exons in the host gene. This ratio is provided in Ratio_RBP_coverage_circRNA_non_circ_exons ((RBP_coverage+ 1)/(mean_RBP_coverage_non_circ_exons+ 1)).