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Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence. Mus musculus

NIAID Data Ecosystem2026-03-09 收录

前列腺癌分子机制

信号通路靶向治疗

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA308659 数据链接链接失效反馈

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资源简介：

we evaluated the mechanism behind NOTCH activation in prostate cancer Overall design: GEP analysis of mice WT, Pten pc+/+; Ptenpc-/-; Ptenpc-/- treated with Gamma-secretase inhibitor

应用场景：

创建时间：

2016-01-13

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To identify the downstream targets and pathways mediated by BRG1, chromatin immunoprecipitation followed by sequencing (ChIP–seq) was performed in control and PTEN-knockdown 22RV-1 cells. Total 6279 g

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Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence. Mus musculus

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