PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 4
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PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 4 Descriptor: (2R,3R,3aS,6S,6aR)-6-[(2-amino-3-bromoquinolin-7-yl)oxy]-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydro-3aH-cyclopenta[b]furan-3,3a-diol, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Palte, R.L, Hayes, R.P. Deposit date: 2020-10-23 Release date: 2021-04-21 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.52 Å) Cite: The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. J.Med.Chem., 64, 2021
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2020-10-23
