Seurat object with the scRNA-Seq dataset of human peripheral blood CD4 T lymphocytes.Donor ID: D11Sex: MaleAge: 43Tissue: Peripheral BloodTissue Details: Sorted CD4 Effector/memory T cells (gated as C
Palmer_KIR3DL3_WTA_TCR.R provides the code for Seurat clustering, multi-modal mapping, and differential expression analysis, alongside the analysis of TCR data, GSEA analysis, and VISION analysis. All
While T cell-based immunotherapies have shown promising clinical responses, current cancer treatments are restricted to autologous cellular products due to the risk of graft-versus-host disease (GvHD)
Data presented as mean (SEM) unless specified. * indicates significant difference between the groups using Student's t-test or Mann-Whitney test if values were not normally distributed.