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Melotenine A, a Cytotoxic Monoterpenoid Indole Alkaloid from <i>Melodinus tenuicaudatus</i>

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NIAID Data Ecosystem2026-03-06 收录
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Melotenine A (1), an unprecedented skeleton with a 6/5/5/6/7 pentacyclic rearranged ring system, was isolated from Melodinus tenuicaudatus. The structure was elucidated by means of spectroscopic methods and further confirmed by the single-crystal X-ray diffraction analysis. A possible biogenesis was also proposed. Melotenine A exhibited potential inhibition against five human cancer cell lines.

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2016-02-25
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