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The role of PRDX1 in chemoresistance

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NIAID Data Ecosystem2026-03-09 收录
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The role of peroxiredoxin 1 in confering chemoresistance in glioma was analysed in a cell culture system. Cells with a lower level of peroxiredoxin 1 showed a higher level of reacitve oxigen species upon treatment with BCNU. In line with this, in a 2D DIGE based redox proteomics approach, proteins were identified showing (1) differences in their thiol state upon knockdown of PRDX1 and (2) proteins showing differences in reduded and unreduced samples.

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2014-12-12
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