Human brain organoids are three-dimensional cultures that recapitulate in vivo cell diversity and organization, which provide a novel source for transplantation therapies of neurological disorders. Ho
How are skeletal tissues derived from skeletal stem cells? Here, we map bone, cartilage, and stromal development from a population of highly pure, postnatal skeletal stem cells (mouse skeletal stem ce
Chimeric antigen receptor (CAR) T cell therapy has achieved remarkable success in hematological malignancies but remains largely ineffective in solid tumors. A major factor leading to the reduced effi
Inhibitory GABAergic interneurons create different brain activity patterns that correlate with behavioral states. In this characterizing study, we used single-cell RNAseq to analyze anatomically- and
BackgroundThis study aimed to investigate the role of integrated stress response (ISR)-related biomarkers in periodontitis (PD). MethodsTranscriptomic data related to PD were obtained from public dat