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Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody

NIAID Data Ecosystem2026-05-02 收录

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数据链接：

https://www.rcsb.org/structure/3J42 数据链接链接失效反馈

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资源简介：

Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody

应用场景：

创建时间：

2024-11-27

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结构药物设计

Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 4 Descriptor: (6-hydroxybiphenyl-3-yl)acetic acid, RNA-directed RNA polymerase NS5, ZINC ION Authors: Noble, C.G. Deposit date: 2016-01

Protein Data Bank Japan2023-11-08 更新60

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation, but resistant to temozolomide (FAIRE-seq). Mus musculus

胶质母细胞瘤模型

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Introduction: Glioma stem cells isolated from human glioblastomas are resistant to radiation and cytotoxic chemotherapy and may drive tumor recurrence. Treatment efficacy may depend on the presence of

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Inhibitory and binding properties of DENV polymerase N-pocket compounds.

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结合特性分析

Inhibitory and binding properties of DENV polymerase N-pocket compounds.

Figshare2016-08-09 更新30

Dengue-RdRp3-inhibitor complex co-crystallisation

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共结晶

Dengue-RdRp3-inhibitor complex co-crystallisation Descriptor: 2-(4-methoxy-3-thiophen-2-yl-phenyl)ethanoic acid, DI(HYDROXYETHYL)ETHER, Genome polyprotein, ... Authors: Talapatra, S.K, Kozielski, F. D

Protein Data Bank Japan2024-01-17 更新60

The structures of six newly designed compounds and their activity against DENV-2 NS2B/NS3pro.

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抗病毒药物研发

The structures of six newly designed compounds and their activity against DENV-2 NS2B/NS3pro.

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