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资源简介：
Tamoxifen-resistant human breast cancer cell lines
应用场景：
创建时间：
2009-12-09
相关数据集
Additional file 9: of Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer
Point mutations from exome-sequencing. Point mutations, sequencing reads and mutation frequency in tamoxifen-resistant cells (Resistant Reference Reads, Resistant Variant Reads, Resistant Variant Freq
NIAID Data Ecosystem60
circRNA sequencing in breast cancer patient tissues
we identified a circular RNA circARHGAP12, which was high-expressed in trastuzumab resistant HER2+ BC tumors and cell lines. We proved that circARHGAP12 promoted trastuzumab resistance by interacting
NIAID Data Ecosystem40
Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance [ChIP-Seq]. Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance [ChIP-Seq]
Cellular plasticity has emerged as an important mechanism of therapy resistance in cancers, yet the underlying molecular mechanisms remain unclear. Using an established breast cancer cellular model fo
NIAID Data Ecosystem20
DataSheet_1_Targeting WEE1 Inhibits Growth of Breast Cancer Cells That Are Resistant to Endocrine Therapy and CDK4/6 Inhibitors.pdf
Despite the success of antiestrogens in extending overall survival of patients with estrogen receptor positive (ER+) breast tumors, resistance to these therapies is prevalent. ER+ tumors that progress
NIAID Data Ecosystem60
Genetic mechanisms of resistance to chemotherapy in breast cancer
Resistance towards chemotherapy is one of the main causes of treatment failure and death among breast cancer patients. The main objective of this project is to identify genetic mechanisms causing some
NIAID Data Ecosystem30
