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Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-700

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Protein Data Bank Japan2026-05-27 更新2026-03-21 收录
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Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-700 Descriptor: (1R)-4-([1,1'-biphenyl]-4-yl)-1-phosphonobutane-1-sulfonic acid, Dehydrosqualene synthase Authors: Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. Deposit date: 2007-11-11 Release date: 2008-03-11 Last modified: 2026-05-27 Method: X-RAY DIFFRACTION (2.03 Å) Cite: A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008

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2007-11-11
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