Haplotype analysis of <i>Ath44</i> on Chr 1.

Genes with DBA-unique sequences (DBA ≠ 129 = B6) within and near the interval of 152.9 - 168.5 Mb are shown. For each gene, expression levels in the aorta and macrophages, amino acid (AA) differences (129, B6-position-DBA), associations with atherosclerosis indicated by GWAS data, and phenotypes of knockout mice are shown. Ratios between two strains that show significant difference in the expression are bolded. AA substitutions that are predicted to be deleterious by SIFT program are bolded (see table S3). a p<0.05, b p<0.01, c p<0.001. A, AKR; Bc, Balb/c; B6, C57BL/6; C, C3H; D, DBA; F, FVB.