Summary of immunohistochemical marker expression in PLum-C orthotopically transplanted tumors with and without androgen.

Adenocarcinoma (Adeno.), sarcomatoid carcinoma (Sarc.). +++ marker present in most or all cells (80%–100%), ++ marker present in many cells (50%–80%), however there are significant numbers of cells that lack expression, + marker present in a minority of cells (5%–50%), +/- marker is present in only rare populations of cells (less than or equal to 5%), - absence of marker. ↑Denotes increased and ↓denotes decreased IHC labeling intensity relative to epithelial cells in adjacent normal prostate. All lung metastasis were CK8+ with variable levels of CK14 expression. CK5 and Vimentin expression was rarely detected, and TP63 and AR expression was not detected.