Transcriptome analysis of naive and Listeria monocytogenes-specific CD8+ T cells
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
The histone methyltransferase Suv39h1 silences transcriptional programs during CD8+-T cell differentiation The study explores the role of gene silencing by Suv39h1, a histone methyltransferase, that plays a critical role in heterochromatin dynamics. Naïve littermate and Suv39h1-KO CD8+ T cells, and day 7 p.i. Kb-OVA+ CD8+ T cells (from Listeria m.-OVA infected mice), were isolated by FACS. RNA was isolated and analyzed using Affymetrix microarrays. microarrays (three mice per condition were analyzed).
创建时间：
2021-07-25
