Univariate analysis for molecular and clinical variables.

Univariate log-rank tests were performed using the newly identified 88-miRNA cluster of failure post-RP and the newly developed predictive salvage radiation therapy (RT) model as well as several clinical factors to determine the ability of each factor to predict time to failure post-radical prostatectomy (RP) and failure post-salvage RT. Prostate specific antigen (PSA) and age were treated as continuous variables whereas other clinical factors were categorized as follows: Gleason score: 6, 7, and ≥8; lymph node: positive or negative; positive surgical margins: R0, R1 and Rx; pathological T stage: (T2, T2a, and T2b), (T2c), and (T3a and T3b); D’Amico risk classification: high and intermediate; Stephensen risk classification: high plus, high, intermediate, and low. n/a, not applicable. Univariate analysis for molecular and clinical variables.