Invasive Haemophilus influenzae (Hi) disease has decreased in countries that included Hi type b (Hib) vaccination in their childhood immunization programs in the 1990s. Non-typeable (NT) and non-b str
*These sequences were not included in the subtype related factors analysis. †5′ half genome sequences. ‡3′ half genome sequences. §Genotype was determined based on all sequences available.
BackgroundThe widespread use of antimicrobials and Haemophilus influenzae type b (Hib) vaccine worldwide has altered the epidemiological patterns of invasive H. influenzae. Nonetheless, little is curr