Abbreviations: ALD = alcohol associated liver disease, AP = alkaline phosphatase, NASH = non alcoholic steatohepatitis, m = male, f = female, y = yes, n = no, uk = unknown. Data are summarised as mean
Malignant peripheral nerve sheath tumors (MPNST) are aggressive soft-tissue sarcomas which lack effective drugs. Loss of the RAS GTPase-activating protein NF1 and subsequent overactivation of mitogen-