After birth, tissues grow continuously until reaching adult size, with each organ exhibiting unique cellular dynamics, growth patterns, and (stem or non-stem) cell sources. Using a suite of experiment

DataCite Commons2025-05-08 更新80

Genome-wide transcriptome profiling of primary human uterine leiomyoma cell populations

肿瘤生物学

干细胞生物学

Uterine leiomyomas (LM) affect up to 80% of all reproductive-age women. LM growth requires progesterone, progesterone receptor (PGR), and the maintenance and proliferation of a small (5%) stem cell po

干细胞与再生医学数据中心2022-02-20 更新140

Gene expression profiling in mouse fibroblast tumors with overexpression of the homeoprotein SIX1. Gene expression profiling in mouse fibroblast tumors with overexpression of the homeoprotein SIX1

基因表达

肿瘤生物学

Six1 is a developmental transcriptional regulator frequently overexpressed in human tumors. Recent results also show that SIX1 acts as a repressor of cell senescence, an antiproliferative response wit

NIAID Data Ecosystem130

Proliferation rate analyzed by Ki-67 antigen expression.

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