Transcriptional profile of MORC3 deficient BLaER1 monocytes [KO]
收藏NIAID Data Ecosystem2026-03-13 收录
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We have identified MORC3 as a negative regulator of Type I Interferon (IFN), whose absence induces IFN and interferon-stimulated genes (ISGs). To study the global transcriptional effects of loss of MORC3, we deleted MORC3 in WT, IFNAR1â/â IFNAR2â/â and IFNB1â/â BLaER1 monocytes and performed RNA-seq. Overall design: Monoclonal gene-deficient BLaER1 monocytes in three independent experiments.
创建时间：
2021-12-03
