Expression data from proliferating and quiescent adult hippocampal neural stem and progenitor cells

We have characterized the transcriptome of adult rat hippocampal neural stem and progenitor cell (NSPC) cultures. The NSPCs cultures can be reversibly arrested by the quiescence-promoting signal BMP4. We provide expression data from NSPCs grown as neurospheres for 4 days in vitro in the presence of FGF2 (proliferating NSPCs) or FGF2+BMP4 (quiescent NSPCs) showing that entry into quiescence involves major changes in the transcriptional profile of the cells. 6 RNA samples were analyzed. Total RNA was isolated from proliferating NSPCs cultured in FGF2 and quiescent NSPCs cultured in FGF2+BMP4, 3 biological replicates for each condition.