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Transcriptional profiles of [ESI+]

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NIAID Data Ecosystem2026-03-11 收录
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We profile the transcriptional landscapes associated with acquisition of [ESI+], a prion scaffolded by Snt1, a core component of the Set3C histone deacetylase. We find that acquisition of [ESI+] leads to expression of otherwise silent, heterochromatic loci, proposing a new molecular means by which silent transcriptional states might be reversed. mRNA sequencing of mid-logarithmically grown naïve and [ESI+] diploid cells

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2020-06-01
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