Isoform switching as a mechanism of acquired resistance to mutant isocitrate dehydrogenase inhibition
收藏NIAID Data Ecosystem2026-03-10 收录
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资源简介：
Targeted next-generation sequencing was performed in patients with IDH1 or IDH2 mutations. Here we describe 4 cases where mutant IDH isoform switching serves as a mechanism of acquired clinical resistance to mutant IDH inhibition.
创建时间：
2018-10-24
