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Targeting ATP2B1 impairs PI3K/Akt/Forkhead box (Fox) transcription factor signaling and reduces SARS-COV-2 infection and replication

ChEBI2024-05-13 更新2026-07-12 收录

新冠病毒抗病毒靶点

PI3K/AKT信号通路调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-13916 数据链接链接失效反馈

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Targeting ATP2B1 impairs PI3K/Akt/Forkhead box (Fox) transcription factor signaling and reduces SARS-COV-2 infection and replication

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创建时间：

2024-05-13

心血管疾病细胞治疗

PI3K/AKT信号通路调控

Aims Endothelial progenitor cells (EPCs) are capable of proliferating and differentiating into mature endothelial cells, and they have been considered as potential candidates for coronary heart diseas

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Fraxetin down-regulates polo-like kinase 4 (PLK4) to inhibit proliferation, migration and invasion of prostate cancer cells through the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway

PI3K/AKT信号通路调控

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Fraxetin, a natural product isolated from herb Cortex Fraxini, has been demonstrated to exhibit anti-cancer effects on various cancers. The aim of this work is to investigate the anti-tumor effect of

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Inhibition of ABI2 Ubiquitination-Dependent Degradation Suppresses Breast Cancer Cell Growth via Down-regulating PI3K/Akt Signaling Pathway [RNAseq-20240420]

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PI3K/AKT信号通路调控

TNBC is a type of cancer that lacks receptor expression and has complex molecular mechanisms. Recent evidence shows that the ubiquitin-protease system is closely related to TNBC. In this study, we obt

NIAID Data Ecosystem20

AcSDKP Regulates Cell Proliferation through the PI3KCA/Akt Signaling Pathway

肿瘤信号通路

PI3K/AKT信号通路调控

The natural tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) is generated from the N-terminus of thymosin-β4 through enzymatic cleavage by prolyl oligopeptidase (POP). AcSDKP regulation of proliferation

Figshare2016-01-18 更新30

PI3K/AKT pathway is activated by miRNA-22 in the proliferative CLL subset (mRNA). Homo sapiens

慢性淋巴细胞白血病增殖亚群

PI3K/AKT信号通路调控

Understanding the crosstalk between malignant B-cells and their milieu could provide clues on the molecular and clinical biology of Chronic Lymphocytic Leukemia (CLL). Aiming to generate novel therape

NIAID Data Ecosystem30

Targeting ATP2B1 impairs PI3K/Akt/Forkhead box (Fox) transcription factor signaling and reduces SARS-COV-2 infection and replication

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