首页/数据集/Chemical characteristics of the best performing classes with PharmaNet.

Chemical characteristics of the best performing classes with PharmaNet.

Figshare2021-04-26 更新2026-04-28 收录

数据链接：

https://figshare.com/articles/dataset/Chemical_characteristics_of_the_best_performing_classes_with_PharmaNet_/14486341 数据链接链接失效反馈

官方服务：

资源简介：

Chemical characteristics of the best performing classes with PharmaNet.

应用场景：

创建时间：

2021-04-26

抗疟药物发现

先导化合物

Malaria is still one of the most prevalent parasitic infections in the world, with half of the world’s population at risk for malaria. The effectiveness of current antimalarial therapies, even that of

Figshare2018-04-05 更新60

Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators

自分泌抑制剂

先导化合物

Autotaxin produces the bioactive lipid lysophosphatidic acid (LPA) and is a drug target of considerable interest for numerous pathologies. We report the expedient, structure-guided evolution of weak p

NIAID Data Ecosystem30

Discovery of Novel MDH2 Inhibitor 28i by Secondary Development of Glibenclamide with Potent Antiaging Activities

抗衰老药物

先导化合物

Aging is a major public health challenge that urgently requires effective pharmacological interventions. We previously identified mitochondrial malate dehydrogenase 2 (MDH2) as a regulator of aging an

Figshare2026-01-23 更新20

R-group replacement resource

药物化学优化

先导化合物

A database with R-groups frequently used in medicinal chemistry and their preferred replacements is provided. For frequently used R-groups, replacements are organized in hierarches as specified in the

NIAID Data Ecosystem30

Lead Optimization of Butyrolactone I as an Orally Bioavailable Antiallergic Agent Targeting FcγRIIB

先导化合物

抗过敏药物研发

Food allergy (FA) poses a growing global food safety concern, yet no effective cure exists in clinics. Previously, we discovered a potent antifood allergy compound, butyrolactone I (BTL-I, 1), from th

Figshare2024-04-19 更新20

Chemical characteristics of the best performing classes with PharmaNet.

资源简介：

相关数据集