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SRCAP Mutations Drive Clonal Hematopoiesis Through Epigenetic and DNA Repair Dysregulation [scRNA-Seq]

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NIAID Data Ecosystem2026-05-01 收录
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To investigate the transcriptomic regulation of Srcap mutant lymphoid-biased expansion after compeititve transplantation We established Srcap heterozygous mutant murine competitive transplantation model. Donor test (CD45.2+) HSPCs in the bone marrow were sored and isolated at 20 weeks post-transplantation for scRNA-seq

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2024-01-18
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