Crystal Structure of Shank2-SAM mutant domain - L1800W

Crystal Structure of Shank2-SAM mutant domain - L1800W Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Bento, I, Gracia Alai, M, Kreienkamp, J.-H. Deposit date: 2022-09-08 Release date: 2022-11-30 Last modified: 2024-09-11 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 29, 2024