Panel NGS sequencing including TP53 from colon/rectal cancer patient using histological FFPE-DNA to identify missense p53 mutants which highly stabilize their p53 protein to increase Stat3 signaling.
The inositol polyphosphate-4-phosphatase type II (INPP4B) has been mostly proposed to act as a tumor suppressor whose expression is frequently dysregulated in numerous human cancers. To date, little i
RNA-Seq was performed after siRNA transfection in ACHN cells. Overall design: After transfection for 48 h, total RNA was extracted using RNAiso Plus. Then,total RNA were identified by deep sequencing,
The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,
Helicobacter pylori (H. pylori) infection is the greatest known risk factor for gastric cancer (GC). Long non-coding RNAs (lncRNAs) are implicated in multiple biological processes. However, their cont